By clicking “Accept All Cookies”, you agree to the storing of cookies on your device to enhance site navigation, analyze site usage, and assist in our marketing efforts. View our Privacy Policy for more information.

Sleeping pill Excedrin PM and its side effects

Carl Heinrichs, owner of Quagga Designs.
Written by,

Carl Heinrichs

CEO of Quagga

Excedrin PM is a commonly used over-the-counter sleeping pill that helps individuals overcome insomnia and achieve a restful night's sleep. However, it is important to be aware of the potential side effects that may accompany its use. Understanding how Excedrin PM works, its active ingredients, and the possible risks involved can help individuals make informed decisions about its use. Quagga Designs bed frame that is completely toxin free is equally important to achieve a good night's sleep.

Understanding Excedrin PM: An Overview

Excedrin PM is a combination medication that contains two active ingredients: acetaminophen and diphenhydramine. This combination helps relieve pain and reduce fever, while also promoting sleep. Available in both tablet and liquid forms, Excedrin PM provides individuals with a convenient solution to their insomnia problems.

Before delving into the side effects, it is crucial to understand how Excedrin PM actually works and the specific roles of its active ingredients.

What is Excedrin PM?

Excedrin PM is a sleep aid that belongs to a class of drugs known as antihistamine analgesic combinations. Through its active ingredients, Excedrin PM helps individuals fall asleep faster and enjoy a longer duration of uninterrupted sleep.

When you take Excedrin PM, the acetaminophen in the medication works to reduce pain and fever by blocking certain chemicals in the body that cause these symptoms. This can provide relief for headaches, muscle aches, and other minor bodily discomforts that may be keeping you awake at night.

Additionally, diphenhydramine, an antihistamine, helps to induce drowsiness and promote sleep. It works by blocking the effects of histamine, a chemical in the body that is involved in wakefulness. By reducing histamine activity, diphenhydramine helps you relax and fall asleep more easily.

Active Ingredients in Excedrin PM

The two primary active ingredients in Excedrin PM are acetaminophen and diphenhydramine. Acetaminophen is a common non-prescription pain reliever that helps alleviate headaches, muscle aches, and minor bodily discomfort. It is a widely used medication known for its effectiveness and safety when used as directed.

Diphenhydramine, on the other hand, is an antihistamine that has sedative properties, making it an effective sleep aid. It is commonly used to treat allergies, but its drowsiness-inducing effects have made it a popular choice for those seeking relief from insomnia. Diphenhydramine is known to have a calming effect on the central nervous system, helping individuals relax and fall asleep more easily.

Together, these ingredients work in harmony to provide individuals with the necessary relief to achieve a good night's sleep. By targeting both pain and sleeplessness, Excedrin PM offers a comprehensive solution for those who struggle with both issues simultaneously.

It is important to note that while Excedrin PM can be an effective sleep aid, it should be used responsibly and as directed. It is always recommended to consult with a healthcare professional before starting any new medication, especially if you have any underlying medical conditions or are taking other medications.

The Science Behind Excedrin PM

Now that we understand the basics of Excedrin PM, let's explore the science behind how it works and the mechanisms it targets to induce sleep.

Excedrin PM, a popular over-the-counter sleep aid, contains a combination of two key ingredients: diphenhydramine and acetaminophen. These ingredients work together to provide not only a restful night's sleep but also relief from pain and inflammation.

How Does Excedrin PM Work?

Excedrin PM works by increasing the levels of certain chemicals in the brain that promote drowsiness and sleep. Specifically, diphenhydramine influences the neurotransmitter histamine to reduce wakefulness and increase feelings of tiredness, leading to a state of relaxation conducive to falling asleep.

When you take Excedrin PM, diphenhydramine enters your bloodstream and crosses the blood-brain barrier. Once in the brain, it binds to histamine receptors, blocking the action of histamine. Histamine is a neurotransmitter that plays a crucial role in regulating wakefulness and sleep. By inhibiting histamine, diphenhydramine helps to promote sleepiness and prepare your body for a restful night's sleep.

In addition to its effects on histamine, diphenhydramine also has anticholinergic properties. This means that it blocks the action of acetylcholine, another neurotransmitter involved in wakefulness. By inhibiting acetylcholine, diphenhydramine further enhances its sleep-inducing effects.

The Role of Acetaminophen and Diphenhydramine

While diphenhydramine primarily acts as the sleep-inducing component in Excedrin PM, acetaminophen assists in providing pain relief and reducing inflammation, allowing individuals to relax and unwind before bedtime.

Acetaminophen, also known as paracetamol, is a common pain reliever and fever reducer. It works by inhibiting the production of prostaglandins, which are chemicals that contribute to pain and inflammation. By reducing the levels of prostaglandins in the body, acetaminophen helps to alleviate headaches, muscle aches, and other discomforts that may interfere with sleep.

In addition to its pain-relieving properties, acetaminophen also has a mild sedative effect. It is thought to influence the brain's pain perception pathways, promoting a sense of calmness and relaxation. By combining these two ingredients, Excedrin PM offers a comprehensive sleep aid that targets both physical and mental factors contributing to insomnia.

It's important to note that while Excedrin PM can be an effective short-term solution for occasional sleeplessness, it is not intended for long-term use. If you are experiencing chronic sleep problems, it is recommended to consult with a healthcare professional to identify and address the underlying causes.

Potential Side Effects of Excedrin PM

Although Excedrin PM can be an effective solution for sleep problems, it is essential to be aware of the potential side effects that may arise from its use. These side effects can vary in severity and occurrence from person to person.

Let's take a closer look at both the common and serious side effects that have been associated with Excedrin PM.

Common Side Effects

The most commonly reported side effects of Excedrin PM include drowsiness, dizziness, and dry mouth. These side effects are typically mild and diminish as the body adjusts to the medication. However, individuals who experience these effects should exercise caution when driving or operating heavy machinery.

Drowsiness is a common side effect of Excedrin PM due to its active ingredient, diphenhydramine, which is a sedating antihistamine. This drowsiness can be beneficial for those seeking relief from sleep problems, but it can also interfere with daily activities that require alertness. It is important to allow enough time for a full night's sleep after taking Excedrin PM to avoid residual drowsiness the next day.

In addition to drowsiness, some individuals may experience dizziness after taking Excedrin PM. This can be attributed to the medication's effect on blood pressure and circulation. It is recommended to avoid sudden movements or activities that require balance until the dizziness subsides.

Dry mouth is another common side effect of Excedrin PM. This occurs because diphenhydramine can reduce saliva production. It is important to stay hydrated and drink plenty of fluids while taking this medication to alleviate any discomfort caused by dry mouth.

Serious Side Effects

While rare, some individuals may experience serious side effects from Excedrin PM. These can include allergic reactions, difficulty breathing, swelling of the face, throat, or tongue, and irregular heartbeat. If any of these symptoms occur, it is crucial to seek medical attention immediately.

Allergic reactions to Excedrin PM can manifest as hives, itching, rash, or even anaphylaxis, a severe and potentially life-threatening allergic reaction. It is important to be aware of any pre-existing allergies and to discontinue use if an allergic reaction occurs.

Difficulty breathing, along with swelling of the face, throat, or tongue, can indicate a severe allergic reaction known as angioedema. This condition requires immediate medical attention, as it can impair breathing and lead to a medical emergency.

In rare cases, Excedrin PM can cause an irregular heartbeat, also known as cardiac arrhythmia. This can manifest as a fast, slow, or irregular heartbeat, palpitations, or chest pain. If any of these symptoms occur, it is important to seek medical attention promptly to assess and manage the cardiac rhythm disturbance.

It is crucial to remember that while Excedrin PM can be an effective solution for sleep problems, it is not suitable for everyone. Individuals with certain medical conditions, such as glaucoma, enlarged prostate, or urinary retention, should avoid taking this medication. Additionally, Excedrin PM should not be used in combination with other sedating medications or alcohol, as it can increase the risk of side effects.

Always consult with a healthcare professional before starting any new medication, including Excedrin PM, to ensure it is safe and appropriate for your specific needs and medical history.

Long-term Use of Excedrin PM

Excedrin PM, a popular over-the-counter sleep aid, is often relied upon by individuals seeking short-term relief from insomnia. However, it is crucial to consider the potential risks associated with prolonged use and the development of dependency on the medication.

Extended use of Excedrin PM can lead to tolerance, a phenomenon where the body becomes accustomed to the medication's effects over time. As tolerance develops, individuals may find that they require higher doses of Excedrin PM to achieve the same sleep-inducing effects they experienced initially. This escalation in dosage can potentially increase the risk of side effects and negatively impact overall health.

Moreover, regular use of Excedrin PM can lead to dependency, a condition where individuals become reliant on the medication to fall asleep. This dependency can develop gradually, as individuals find it increasingly difficult to initiate sleep without the aid of Excedrin PM. This reliance on the medication can have significant implications for one's sleep patterns and overall well-being.

It is important to note that discontinuing the use of Excedrin PM abruptly can result in withdrawal symptoms. These symptoms may include restlessness, irritability, and difficulty sleeping. The severity and duration of withdrawal symptoms can vary from person to person, making it crucial to consult a healthcare professional before making any changes to your sleep aid routine.

In conclusion, while Excedrin PM can provide short-term relief for insomnia, it is essential to be aware of the potential risks associated with prolonged use and the development of dependency. Consulting a healthcare professional can help guide individuals in making informed decisions about their sleep aid routine and overall sleep health.

Alternatives to Excedrin PM

For individuals who are concerned about the potential side effects or long-term use of Excedrin PM, there are alternative options to explore, both natural and prescription-based.

Natural Sleep Aids

Natural sleep aids, such as melatonin or herbal supplements like valerian root or chamomile, can provide a gentle and non-addictive approach to promoting sleep. These options offer a viable alternative for those seeking relief from insomnia without the potential risks associated with regular medication use.

Prescription Sleep Medications

If natural remedies are not effective, consulting with a healthcare professional about prescription sleep medications may be a suitable option. These medications can provide targeted relief for individuals struggling with chronic insomnia, but they should be used under professional guidance to minimize potential risks and side effects.

Overall, Excedrin PM can be an effective sleep aid for short-term use when used responsibly. Understanding its active ingredients, mechanism of action, and potential side effects can help individuals make informed decisions about its use and explore alternative options if needed. It is always important to consult with a healthcare professional before starting any new sleep aid regimen to ensure that it aligns with your specific needs and health condition.

As you consider the importance of a good night's sleep and the potential side effects of sleep aids like Excedrin PM, remember that your sleep environment plays a crucial role in your sleep quality. Quagga Designs offers a range of easy-to-assemble, MADE IN CANADA bed frames that can transform your bedroom into a haven of rest. Our No-Fuss Plus and Tic-Tac-Toe beds require no hardware for assembly, and you can set them up in less time than it takes to unbox. With the No-Fuss Plus bed's ability to expand from single to double and queen to king size, and the Accordion bed's versatility across multiple mattress sizes, you'll never need to buy a new frame when upgrading your mattress—reducing landfill and supporting our local economy. Crafted with all-natural soy-based glue and FSC Certified Maple and Mahogany woods, our environmentally clean bed frames are a responsible choice for a sustainable lifestyle. Plus, with our 100 night sleep trial, 5-year warranty, and customizable design, you can rest assured that your Quagga bed frame is a sound investment. Check out our products and experience the difference a Quagga Designs bed frame can make in your life.

Carl Heinrichs

CEO of Quagga
Carl Heinrichs is the Founder of Quagga, Canada's most innovative furniture design solutions that are easy to assemble and playfully made.

Recent Blog Posts